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We describe a family in which the father had neurofibromatosis-1 and the mother neurofibromatosis-2.Their son presented at the age of 8 years with bilateral acoustic neuromas,meningioma,and numerous neurofibromas.We believe that the occurrence of the genes responsible for both forms of neurofibromatosis in the same patient had a synergistic effect on the early rapid growth of neurofibromatosis 1 and 2 neoplasms. |
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